Treadmill running improves spatial learning and memory in the rats with intracerebroventricular injection of streptozotocin
نویسندگان
چکیده
1Student, Department of Basic Sciences, Isfahan Payame Noor University, Isfahan, Iran 2Assistant Professor, Biosensor Research Center and Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 3Professor, Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran 4Assistant Professor, Department of Basic Sciences, Isfahan Payame Noor University, Isfahan, Iran 5Assistant Professor, Department of Anatomical Sciences and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Corresponding Author: Parham Reisi E-mail: [email protected]
منابع مشابه
The Effect of Aqueous Crocus sativus L. Extract on Intracerebroventricular Streptozotocin-induced Cognitive Deficits in Rat: a Behavioral Analysis
Intracerebroventricular (ICV) injection of streptozotocin (STZ) causes cognitive impairment in rats. The beneficial effect of Crocus sativus L. extract (CSE) was evaluated on ICV STZ-induced learning, memory, and cognitive impairment in male rats. For this purpose, rats were injected with ICV STZ bilaterally, on days 1 and 3 (3 mg/kg). The STZ-injected rats received CSE (60 mg/kg; i.p.) every o...
متن کاملThe Effect of Aqueous Crocus sativus L. Extract on Intracerebroventricular Streptozotocin-induced Cognitive Deficits in Rat: a Behavioral Analysis
Intracerebroventricular (ICV) injection of streptozotocin (STZ) causes cognitive impairment in rats. The beneficial effect of Crocus sativus L. extract (CSE) was evaluated on ICV STZ-induced learning, memory, and cognitive impairment in male rats. For this purpose, rats were injected with ICV STZ bilaterally, on days 1 and 3 (3 mg/kg). The STZ-injected rats received CSE (60 mg/kg; i.p.) every o...
متن کاملThe effect of chlorogenic acid on learning and memory and acetylchoinesterase activity in rats with cognitive deficit induced by intracerebroventricular streptozotocin
Background and Objective: Chlorogenic acid (CGA) is a major polyphenolic component of coffee. Reduction in the risk of a variety of diseases following CGA consumption has been mentioned in recent studies. The effect of CGA on learning and memory in rats with cognitive deficit induced by intracerebroventricular streptozotocin (STZ) and acetylchoinesterase (AChE) activity was evaluated in this s...
متن کاملMefenamic Acid Attenuates Intracerebroventricular Streptozotocin-Induced Cognitive Deficits in the Rat: A Behavioral Analysis
Intracerebroventricular (ICV) injection of streptozotocin (STZ) in rats is followed by long-term and progressive deficits in learning, memory, and cognitive performance which is somewhat similar to sporadic Alzheimer’s disease (SAD). Epidemiological studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) could delay or slow the clinical expression of SAD. Therefore, the benefi...
متن کاملL-carnosine Improves Short-Term Spatial Recognition Memory and Passive Avoidance Learning and Memory in Streptozotocin-Diabetic Rats
Background and Objective: Diabetes mellitus (DM) affects synaptic plasticity in the hippocampus, leading to impairments in learning and memory. L-carnosine, an endogenous dipeptide, is reported to exhibit anti-diabetic and antioxidant effects. Therefore, this study was designed to evaluate its effect on learning and memory in diabetic rats. Materials and Methods: In the present study, male Wis...
متن کاملThe effect of genistein on intracerebroventricular streptozotocin-induced cognitive deficits in male rat
Abstract Introduction: Intracerebroventricular (ICV) injection of streptozotocin (STZ) causes cognitive impairment in rats. The beneficial effect of genistein (GEN) was investigated on ICV STZ-induced learning, memory, and cognitive impairment in male rats. Methods: For this purpose, rats were injected with ICV STZ bilaterally, on days 1 and 3 (3 mg/kg). The STZ-injected rats received GEN (1...
متن کامل